Widespread posttranslational modifications include methylation of the ε-amino group, giving methyl- , dimethyl- , and trimethyllysine The latter occurs in calmodulin Other posttranslational modifications at lysine residues include acetylation , sumoylation , and ubiquitination Collagen comprises hydroxylysine , which is derived from lysine by lysyl hydroxylase - Glycosylation of hydroxylysine residues within the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell In opsins like rhodopsin and the visual opsins (encoded by the genes OPN1SW , OPN1MW , and OPN1LW ), retinaldehyde forms a Schiff base with a conserved lysine residue, and interaction of sunshine with the retinylidene group causes sign transduction in coloration vision (See visual cycle for details).
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